Scales to Play Over D#sus4

Every chord is a subset of several scales: any scale that contains all of a chord's tones fits over it. Pick a chord to see the matching scales from its own root, the major keys the chord belongs to, and full fretboard diagrams for every scale on guitar.

A D#sus4 chord contains the notes D# – G# – A#. Any scale that includes every one of those 3 tones fits over it — from the root D#, that means D# Major, D# Natural Minor, D# Melodic Minor, D# Harmonic Minor, D# Minor Pentatonic, D# Blues, D# Dorian, D# Phrygian, D# Mixolydian, D# Dorian Bebop, D# Mixolydian Bebop and D# Spanish. Start with the first scale listed: it is the most common choice, and the others color the same chord tones differently.

D#sus4 is also diatonic to 5 major keys: B major (relative minor G#m), C# major (relative minor A#m), D# major (relative minor Cm), F# major (relative minor D#m), G# major (relative minor Fm). In a song from one of those keys you can also solo with the key's own major scale or its relative minor pentatonic across the whole progression, not just this chord.